It has been estimated that drug related crimes currently account for roughly one third of the U.S. prison population. At the same time, prescription drug sales continue to skyrocket, with a particularly sharp increase over the past decade (up by about 250 percent). The distinction between legal and illegal drugs (and the respective bureaucracies that flourished around it) has produced highly lucrative spheres: prisons overwhelmingly populated by drug offenders, a major (primarily U.S.) market for illegal drugs, and, at the same time, an ever-expanding arena of R&D, patenting, and marketing for pharmaceuticals (tested on those desperate enough to enter clinical trials, enjoyed by those able to afford them).