“In terms of microdosing, what we really need are controlled clinical trials, and we don’t have any,” he explains. Some microdosers claim the practice can enhance productivity, focus and mood. Ayelet Waldman, who recently published A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage and My Life, asserts that microdosing on LSD helped her overcome depression and bipolar disorder. “I was suicidal, and now I’m not dead,” Waldman says.